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CIN 1 and CIN 3 HSIL what does this mean?

Cervical Cancer research and treatment discussions

CIN 1 and CIN 3 HSIL what does this mean?

Postby athemar » Mon Oct 29, 2012 4:16 am

I got some pap smear results back it said something about HPV CIN 1 and CIN3 HSIL what does all this mean?

Is HPV the same things is genital warts?
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CIN 1 and CIN 3 HSIL what does this mean?

Postby herve » Mon Oct 29, 2012 4:31 am

Human Papilloma Virus (HPV) has different types. Some may cause genital warts and some may cause cervical cancer.

CIN 1: Mild cervical intraepithelial neoplasia

CIN3: Severe cervical intraepithelial dysplasia to carcinoma in situ

HSIL: High-grade squamous intraepithelial lesion

Since your Pap Smear came back with a CIN3, it's important you go to the doctor as soon as possible to determine your treatment.
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CIN 1 and CIN 3 HSIL what does this mean?

Postby morio20 » Mon Oct 29, 2012 4:38 am

Genital warts are caused by an HPV type. HPV types are numbered. They are 40 HPV types. Some do cause genital warts and some cause abnormal cell changes of the cervix some HPV types can cause both. Genital warts usually occur on the external genital area. Your Pap smear is a collection of cells of the cervix. HPV is showing on the cervix. No cells are collected of the external vulva tissues when our doctor collects the cells of our cervix. The cell changes of CIN 1 and CIN 3 are caused by high risk HPV types. CIN 1 is mild cell changes and is not usually treated. CIN 3 is true pre-cancer cell changes and is treated due to the higher risk that these cell changes could progress. .

Your doctor may want to do a colposcope before any treatment taking a biopsy of the area that is CIN 3 this will confirm that the cell changes are true pre-cancer cell changes. Your doctor will recommend a treatment that will remove the cell changes. Removing the cell changes can prevent most all cervical cancers. Your doctor may go forward with the removal of the cells. Your doctor will recommend when he feels you need to have your next Pap test. Most doctors will follow a person with CIN 3 a bit closer for a year or two.

Low-grade squamous intraepithelial lesions (LSILs) are considered mild abnormalities caused by HPV infection. Low-grade means that there are early changes in the size and shape of cells. Intraepithelial refers to the layer of cells that forms the surface of the cervix. LSILs are sometimes classified as mild dysplasia. LSILs may also be classified as cervical intraepithelial neoplasia (CIN-1).
High-grade squamous intraepithelial lesions (HSILs) are more severe abnormalities that have a higher likelihood of progressing to cancer if left untreated. High-grade means that there are more evident changes in the size and shape of the abnormal (precancerous) cells and that the cells look very different from normal cells. HSILs include lesions with moderate or severe dysplasia and carcinoma in situ (CIS). HSIL lesions are sometimes classified as CIN-2, CIN-3, or CIN-2/3. CIS is commonly included in the CIN-3 category
http://www.cancer.gov/cancertopics/factsheet/detection/Pap-HPV-testing
Understanding cervical cell changes
http://www.cancer.gov/cancertopics/understandingcervicalchanges/page1
Most HPV lesions eventually resolve due to a host immune response to the virus. This is particularly true for genital warts and CIN1 because neither are truly precancer. Even approximately 40-50% of CIN2 will resolve spontaneously. CIN3 is considered a true cancer precursor, although some CIN3 may also resolve secondary to an immune mediated regression.
http://www.asccp.org/PracticeManagement/HPV/NaturalHistoryofHPV/tabid/5962/Default.aspx
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CIN 1 and CIN 3 HSIL what does this mean?

Postby chanti24 » Mon Oct 29, 2012 4:41 am

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