Lung Cancer Protein TIAM1

New Research Helps Understand Lung Cancer Progression

Lung Cancer Protein TIAM1

Lung Cancer Protein TIAM1

According to the American Lung Association, lung cancer remains the leading cancer killer in both men and women. With many Americans having a long history of smoking cigarettes that is unlikely to change soon. A staggering 159,260 Americans will die from lung cancer in 2014, which is approximately 27% of all cancer deaths. Over 400,000 Americans are currently battling lung cancer.

Unfortunately lung cancer is both prevalent and extremely dangerous, remaining one of the most deadly forms of the disease. The amount of damage that lung cancer has caused our society is massive and it is expected to continue for many years because of cigarette usage. Surprisingly, cigarette usage is increasing in many parts of the world!

Thankfully, some new research will help specialists understand how lung cancer spreads, potentially leading to new treatments. Researchers found that lung cancer cells had severed proteins, which helped them separate and proliferate through the body. While cells do normally separate, cancer cells are especially prone to cell separation.

By understanding how these proteins work, researchers believe they may be able to prevent cancer cells from metastasizing. One protein link which is important in the functioning of lung cancer is TIAM1. TIAM1 helps determine how strong the links are between cancer cells in the lungs.

Lead researcher Dr. Angeliki Malliri explains: “This important research shows for the first time how lung cancer cells sever ties with their neighbors and start to spread around the body, by hijacking the cells’ recycling process and sending it into overdrive. Targeting this flaw could help stop lung cancer from spreading,”

If drugs can be developed to change the way specific proteins function, researchers may develop drugs that completely stop lung cancer from spreading. If the research comes to fruition, it could save millions of lives.

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